SLU-PP-332 is an oral synthetic ERRa agonist discovered at Saint Louis University. Unlike hormones or stimulants, it potently activates ERRa, a transcriptional master regulator of cellular energy metabolism in tissues like muscle and heart. By binding ERRa, it upregulates programs for mitochondrial biogenesis, fatty acid oxidation, and oxidative phosphorylation. A capsule formulation is the likely delivery method for human use.
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